Endocrine Abstracts

Background and aimsMonogenic forms of diabetes caused by a single gene defect include maturity onset diabetes of the young (MODY), neonatal diabetes mellitus and syndromic forms. They are estimated to account for 1–3% of all diabetes cases, but the prevalence is higher among pediatric patients without islet autoantibodies (AAB). Despite presenting with insulin deficiency, many patients can be treated with anti-hyperglycaemic agents to stimulate the...

ObjectiveTo study the predictive value of autoantibodies in progression to type 1 (T1DM) and type 2 (T2DM) diabetes after gestational diabetes (GDM) in a 23-year follow-up study. BackgroundWomen with GDM are at high risk for T2DM later in life, but also the risk of T1DM is increased. We have previously reported a prospective 6-year cohort study showing an association of islet cell and glutamic acid decarboxyl...